Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.
| Version: | 0.1.0 |
| Imports: | Iso |
| Published: | 2018-09-28 |
| DOI: | 10.32614/CRAN.package.titeIR |
| Author: | Lee McDaniel [aut, cre] |
| Maintainer: | Lee McDaniel <lmcda4 at lsuhsc.edu> |
| License: | GPL-3 |
| NeedsCompilation: | no |
| CRAN checks: | titeIR results |
| Reference manual: | titeIR.html , titeIR.pdf |
| Package source: | titeIR_0.1.0.tar.gz |
| Windows binaries: | r-devel: titeIR_0.1.0.zip, r-release: titeIR_0.1.0.zip, r-oldrel: titeIR_0.1.0.zip |
| macOS binaries: | r-release (arm64): titeIR_0.1.0.tgz, r-oldrel (arm64): titeIR_0.1.0.tgz, r-release (x86_64): titeIR_0.1.0.tgz, r-oldrel (x86_64): titeIR_0.1.0.tgz |
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