Bayesian and Adaptive Clinical Trial Simulation and Monitoring


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Documentation for package ‘AdaptiveTrialsR’ version 0.1.2

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adaptive_randomisation Adaptive Randomisation Probabilities
analyse_trial_data Analyse Real Trial Data Using Bayesian Monitoring
compare_trial_scenarios Compare Operating Characteristics Across Trial Scenarios
create_trial_template Create a Trial Data Template
crm_dose_finding Simple Bayesian CRM Dose-Finding Summary
decision_summary Summarise Final Decisions from Adaptive Trial Simulations
estimate_treatment_effect Estimate Bayesian Treatment Effect for Binary Trial Outcomes
export_figures_to_desktop Export a Figures Directory
export_trial_results Export Adaptive Trial Simulation Results
group_sequential_boundary Group Sequential Monitoring Boundaries
interim_monitoring Bayesian Interim Monitoring for Adaptive Clinical Trials
plot_dose_finding Plot Bayesian Dose-Finding Results
plot_group_sequential_boundary Plot Group Sequential Monitoring Boundaries
plot_operating_characteristics Plot Operating Characteristics from Simulated Adaptive Trials
plot_posterior_density Plot Posterior Density for Trial Arms
plot_posterior_intervals Plot Posterior Credible Intervals for Trial Arms
plot_real_trial_results Plot Real Trial Analysis Results
plot_sample_size_distribution Plot Sample Size Distribution from Adaptive Trial Simulations
plot_scenario_comparison Plot Scenario Comparison for Adaptive Trial Simulations
plot_treatment_effect Plot Bayesian Treatment Effect
plot_trial_path Plot Interim Monitoring Path for an Adaptive Trial
posterior_summary Posterior Summary for Binary Trial Outcomes
predictive_probability Predictive Probability of Trial Success
predict_success Predict Bayesian Probability of Trial Success
sample_size_binary Sample Size for Two-Arm Binary Endpoint Trial
simon_two_stage Simon Two-Stage Phase II Trial Design
simulate_trial Simulate a Bayesian Adaptive Clinical Trial
simulate_trials Simulate Multiple Bayesian Adaptive Clinical Trials
summary_trial Summarise a Simulated Adaptive Trial
trial_report Create a Trial Report
validate_trial_data Validate Real Trial Data for Adaptive Trial Analysis